Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993364 | 0.90 | KMT2A (0.47) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL213297 | 0.82 | MAPT (0.47) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL213296 | 0.82 | MAPT (0.47) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL4743743 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL10984538 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL11310744 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL3279914 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL7626647 | 0.76 | BCHE (0.46) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL6474700 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 | |
| SCHEMBL14164367 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPK1SMN1; SMN2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912536-B1 | TAXANE HYDROXY MONOACYLATION METHOD | AVENTIS PHARMA SA (FR) | 2002-06-05 | — | — | EP | claimed |
| EP-0912536-A1 | TAXANE HYDROXY MONOACYLATION METHOD | Aventis Pharma S.A. (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998001435-A1 | TAXANE HYDROXY MONOACYLATION METHOD | RHONE-POULENC RORER S.A. (FR) | 1998-01-15 | — | — | WO | claimed |
| EP-0912536-B1 | TAXANE HYDROXY MONOACYLATION METHOD | AVENTIS PHARMA SA (FR) | 2002-06-05 | — | — | EP | disclosed |
| EP-0912536-A1 | TAXANE HYDROXY MONOACYLATION METHOD | Aventis Pharma S.A. (FR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001435-A1 | TAXANE HYDROXY MONOACYLATION METHOD | RHONE-POULENC RORER S.A. (FR) | 1998-01-15 | — | — | WO | disclosed |