Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509550 | 0.91 | TDP1 (0.45) | RAB9AHSD11B1SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL28422807 | 0.84 | CES2 (0.52) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL5796647 | 0.83 | NAAA (0.43) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL13267740 | 0.81 | CES2 (0.50) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL162772 | 0.81 | CES2 (0.50) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL10272245 | 0.81 | CES2 (0.50) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL1228534 | 0.81 | CES2 (0.50) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL12923059 | 0.81 | CES2 (0.50) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL599277 | 0.81 | CES2 (0.55) | CES2CES1NAAAHDAC8HDAC6 | |
| SCHEMBL28425729 | 0.81 | CES2 (0.55) | CES2CES1NAAAHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638597-B2 | Removal of metal contaminants from polyethylene | EQUISTAR CHEMICALS, LP (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638597-B2 | Removal of metal contaminants from polyethylene | EQUISTAR CHEMICALS, LP (US) | 2009-12-29 | — | — | US | disclosed |
| US-20090152169-A1 | Removal of metal contaminants from polyethylene | EQUISTAR CHEMICALS, LP | 2009-06-18 | — | — | US | disclosed |
| US-20090152169-A1 | Removal of metal contaminants from polyethylene | EQUISTAR CHEMICALS, LP | 2009-06-18 | — | — | US | disclosed |
| US-4533673-A | 7-Oxabicycloheptane substituted enaminone prostaglandin analogs and their use in treatment of thrombolytic disease | E. R. SQUIBB & SONS, INC. (US) | 1985-08-06 | — | — | US | disclosed |