Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992280 | 0.86 | CYP3A4 (0.60) | CYP3A4L3MBTL1TP53GAATSHR | |
| SCHEMBL10994321 | 0.84 | CYP3A4 (0.52) | CYP3A4TP53GAATSHRLMNA | |
| SCHEMBL6733814 | 0.82 | GRM2 (0.62) | CYP3A4L3MBTL1TP53GAATSHR | |
| SCHEMBL10985093 | 0.80 | LTB4R2 (0.54) | CYP3A4L3MBTL1LMNA | |
| SCHEMBL10989044 | 0.80 | MAPT (0.63) | CYP3A4TP53LMNAMAPT | |
| SCHEMBL7748091 | 0.80 | TBXAS1 (0.62) | CYP3A4L3MBTL1TP53GAATSHR | |
| SCHEMBL7748094 | 0.80 | TBXAS1 (0.62) | CYP3A4L3MBTL1TP53GAATSHR | |
| SCHEMBL25797239 | 0.79 | CYP3A4 (0.53) | CYP3A4L3MBTL1TP53LMNACHRNB2 | |
| SCHEMBL10990555 | 0.78 | CYP3A4 (0.47) | CYP3A4TP53GAATSHRLMNA | |
| SCHEMBL27532609 | 0.77 | CYP3A4 (0.50) | CYP3A4GAACHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501746-A | HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |