Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992341 | 0.81 | MAOB (0.49) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL24359756 | 0.81 | RAB9A (0.49) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL3334045 | 0.78 | MEN1 (0.47) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL16826158 | 0.78 | RAB9A (0.49) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL30385939 | 0.78 | MEN1 (0.47) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL11630165 | 0.78 | MAOB (0.46) | RAB9AALDH1A1NPC1MAPTIDO1 | |
| SCHEMBL28994891 | 0.77 | MAOB (0.50) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL30310041 | 0.77 | MAOB (0.50) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL4901305 | 0.76 | KMO (0.58) | RAB9AALDH1A1NPC1MAPTIDO1 | |
| SCHEMBL10843744 | 0.76 | CYP2A6 (0.42) | MAOBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503056-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1985-03-05 | — | — | US | disclosed |
| US-4112095-A | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1978-09-05 | — | — | US | disclosed |