Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986787 | 0.86 | KDM4E (0.41) | KDM4EMEN1KMT2A | |
| SCHEMBL281949 | 0.82 | MAPT (0.35) | MAPTCDC25AGAAKDM4EALDH1A1 | |
| SCHEMBL10983369 | 0.82 | GAA (0.46) | GAAKDM4EALDH1A1KMT2AAADAT | |
| SCHEMBL281245 | 0.79 | ALDH1A1 (0.36) | MAPTSCN9ACDC25AGAAALDH1A1 | |
| SCHEMBL281678 | 0.78 | SCN9A (0.45) | SCN9AGAAKDM4EALDH1A1 | |
| SCHEMBL10826562 | 0.70 | CA12 (0.45) | SCN9ACDC25AKDM4EALDH1A1MEN1 | |
| SCHEMBL29915854 | 0.70 | CHEK1 (0.49) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL9952138 | 0.70 | CHEK1 (0.49) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL281797 | 0.69 | CES1 (0.51) | GAAKDM4EALDH1A1MEN1KMT2A | |
| Doliracetam SCHEMBL2110097 | 0.69 | CYP2C19 (0.55) | SCN9ACDC25AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542148-A | 2-Oxo-3-phenyl indole derivatives, drugs having a neuroanabolic action containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |