Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP10 | Q14694 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748508 | 0.79 | MAPT (0.53) | TDP1ATMMAPTL3MBTL1MAPK1 | |
| SCHEMBL9603355 | 0.77 | TDP1 (0.49) | TDP1ATMUSP10USP7USP47 | |
| SCHEMBL1151368 | 0.75 | ATM (0.58) | TDP1ATMUSP10USP7USP47 | |
| SCHEMBL29662268 | 0.75 | ATM (0.58) | TDP1ATMUSP10USP7USP47 | |
| SCHEMBL27225074 | 0.72 | GSTP1 (0.54) | TDP1ATMMAPTMAPK1ALDH1A1 | |
| SCHEMBL3199054 | 0.72 | ALDH1A1 (0.64) | TDP1ATMMAPTL3MBTL1MAPK1 | |
| SCHEMBL14577163 | 0.72 | ATM (0.55) | TDP1ATMUSP10USP7USP47 | |
| SCHEMBL21183179 | 0.72 | ALDH1A1 (0.36) | MAPTL3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL29380481 | 0.72 | ATM (0.55) | TDP1ATMUSP10USP7USP47 | |
| SCHEMBL21445773 | 0.71 | ATM (0.53) | TDP1ATMUSP10USP7USP47 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548640-A | BROADLEAF WEEDS, SAFE FOR CROPS | FMC CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |