Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | USP10 | Q14694 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985488 | 0.77 | TDP1 (0.46) | TDP1ATMPDE7AMAPTALDH1A1 | |
| SCHEMBL27225074 | 0.75 | GSTP1 (0.54) | TDP1ATMMAPTALDH1A1KMT2A | |
| SCHEMBL29662268 | 0.74 | ATM (0.58) | TDP1ATMPDE7AMAPTALDH1A1 | |
| SCHEMBL1151368 | 0.74 | ATM (0.58) | TDP1ATMPDE7AMAPTALDH1A1 | |
| SCHEMBL310240 | 0.73 | ATM (0.53) | TDP1ATMPDE7AMAPTALDH1A1 | |
| SCHEMBL8595244 | 0.73 | KMT2A (0.39) | PDE7AMAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6687021 | 0.72 | THRB (0.41) | MAPTALDH1A1KMT2AL3MBTL1RAB9A | |
| SCHEMBL9443340 | 0.71 | TSHR (0.45) | TDP1PDE7AMAPTALDH1A1KMT2A | |
| SCHEMBL26931230 | 0.71 | TDP1 (0.50) | TDP1ATMPDE7AMAPTALDH1A1 | |
| SCHEMBL8595123 | 0.71 | EGFR (0.36) | TDP1PDE7AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185025-A | SUBSTITUTED PYRAZOLES AND THEIR USE AS HERBICIDES | MONSANTO COMPANY (US) | 1993-02-09 | — | — | US | disclosed |
| US-5045106-A | 3-phenoxypyrazole | MONSANTO COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0371947-A1 | Substituted pyrazoles and their use as herbicides | Monsanto Company (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0370990-A1 | Herbicidal substituted pyrazoles | MONSANTO COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0295233-A2 | Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides | Monsanto Company (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4548640-A | BROADLEAF WEEDS, SAFE FOR CROPS | FMC CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |