Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988916 | 0.83 | TSPO (0.48) | MEN1KMT2ARAB9AALDH1A1HTT | |
| SCHEMBL30539311 | 0.83 | TSPO (0.65) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL1170339 | 0.83 | TSPO (0.65) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL10985687 | 0.83 | TSPO (0.65) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL10987741 | 0.83 | TSPO (0.65) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL5973200 | 0.83 | RAB9A (0.48) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL10987019 | 0.82 | ERCC1 (0.49) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL10987066 | 0.82 | RAB9A (0.47) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL10990228 | 0.81 | RAB9A (0.45) | MEN1KMT2ATP53RAB9AALDH1A1 | |
| SCHEMBL3039437 | 0.79 | TSPO (0.52) | MEN1KMT2ATP53RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499094-A | PREVENTION OF RESPIRATORY, UROGENITAL, CARDIOVASCULAR AND IMMUNOLOGICAL DISORDERS WHEN USING FOR BENZDIAPINES | PHARMUKA LABORATOIRES (FR) | 1985-02-12 | — | — | US | disclosed |