Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK25 | O00506 | 4/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981098 | 0.84 | STK25 (0.54) | STK25MAPK14CNR2MAPK13IGF1R | |
| SCHEMBL10983612 | 0.84 | STK25 (0.48) | STK25MAPK14CNR2MAPK13 | |
| SCHEMBL11032002 | 0.83 | MAPK14 (0.53) | STK25MAPK14CNR2BRAFMAPK13 | |
| SCHEMBL11001220 | 0.83 | MAPK14 (0.53) | STK25MAPK14CNR2BRAFMAPK13 | |
| SCHEMBL10978951 | 0.81 | MAPK14 (0.52) | STK25MAPK14CNR2BRAFMAPK13 | |
| SCHEMBL11002553 | 0.81 | MAPK14 (0.52) | STK25MAPK14CNR2BRAFMAPK13 | |
| SCHEMBL10982800 | 0.81 | STK25 (0.48) | STK25MAPK14CNR2MAPK13 | |
| SCHEMBL10980404 | 0.81 | STK25 (0.48) | STK25MAPK14CNR2BRAFMAPK13 | |
| SCHEMBL10981419 | 0.80 | STK25 (0.47) | STK25MAPK14CNR2MAPK13JAK3 | |
| SCHEMBL10979074 | 0.80 | STK25 (0.47) | STK25MAPK14CNR2BRAFMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501606-A | Herbicidal 5-t-butyl-3-pyrazalylcarbamates and ureas | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1985-02-26 | — | — | US | claimed |
| JP-58144373-A | — | — | None | — | — | JP | disclosed |
| US-4501606-A | Herbicidal 5-t-butyl-3-pyrazalylcarbamates and ureas | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1985-02-26 | — | — | US | disclosed |
| JP-S58144373-A | PYRAZOLYLCARBAMIC ACID ESTER DERIVATIVE, ITS PREPARATION AND HERBICIDE | SHOWA DENKO KK | 1983-08-27 | — | — | JP | disclosed |