Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | STK25 | O00506 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032002 | 0.86 | MAPK14 (0.53) | MAPK14STK25CNR2KDRMAPK13 | |
| SCHEMBL11002553 | 0.84 | MAPK14 (0.52) | MAPK14STK25CNR2KDRL3MBTL1 | |
| SCHEMBL11008356 | 0.83 | MAPK14 (0.49) | MAPK14STK25RAB9ANPC1NR1I2 | |
| SCHEMBL10985695 | 0.83 | STK25 (0.52) | MAPK14STK25CNR2KDRMAPK13 | |
| SCHEMBL11002888 | 0.81 | STK25 (0.54) | MAPK14STK25SMN1; SMN2CNR2KDR | |
| SCHEMBL11002244 | 0.81 | MAPK14 (0.53) | MAPK14STK25RAB9ANPC1NR1I2 | |
| SCHEMBL10979715 | 0.81 | MAPK14 (0.50) | MAPK14STK25CNR2MAPK13CSNK1A1 | |
| SCHEMBL11004998 | 0.81 | MAPK14 (0.53) | MAPK14STK25CNR2MAPK13CSNK1A1 | |
| SCHEMBL11005613 | 0.80 | MAPK14 (0.55) | MAPK14STK25RAB9ANPC1NR1I2 | |
| SCHEMBL11002662 | 0.80 | EGFR (0.54) | MAPK14STK25SMN1; SMN2CNR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505739-A | Herbicidal 5-t-butyl-3-(N-alkanoylamino)pyrazoles | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1985-03-19 | — | — | US | disclosed |