Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | STK25 | O00506 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001220 | 0.86 | MAPK14 (0.53) | MAPK14STK25CNR2BRAFMAPK13 | |
| SCHEMBL10978951 | 0.84 | MAPK14 (0.52) | MAPK14STK25CNR2CCNA2CDK2 | |
| SCHEMBL11002553 | 0.84 | MAPK14 (0.52) | MAPK14STK25CNR2BRAFMAPK13 | |
| SCHEMBL10985695 | 0.83 | STK25 (0.52) | MAPK14STK25CNR2BRAFMAPK13 | |
| SCHEMBL11002888 | 0.81 | STK25 (0.54) | MAPK14STK25CNR2CCNA2CDK2 | |
| SCHEMBL10979715 | 0.81 | MAPK14 (0.50) | MAPK14STK25CNR2BRAFMAPK13 | |
| SCHEMBL11002244 | 0.81 | MAPK14 (0.53) | MAPK14STK25CNR2BRAFMAPK13 | |
| SCHEMBL11004998 | 0.81 | MAPK14 (0.53) | MAPK14STK25CNR2CCNA2CDK2 | |
| SCHEMBL10929033 | 0.81 | MAPK14 (0.47) | MAPK14STK25CNR2JAK3BTK | |
| SCHEMBL10929026 | 0.81 | MAPK14 (0.47) | MAPK14STK25CNR2JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545809-A | Herbicidal N-(5-t-butyl-3-pyrazolyl) carbamates | SDS BIOTECH K.K. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4501606-A | Herbicidal 5-t-butyl-3-pyrazalylcarbamates and ureas | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1985-02-26 | — | — | US | disclosed |
| US-4501606-A | Herbicidal 5-t-butyl-3-pyrazalylcarbamates and ureas | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1985-02-26 | — | — | US | disclosed |