Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985186 | 1.00 | HTR2A (0.45) | HTR2AMTNR1ACYP2D6MTNR1BMAOA | |
| SCHEMBL3918191 | 0.81 | MTNR1A (0.49) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A | |
| SCHEMBL3918187 | 0.81 | MTNR1A (0.49) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A | |
| SCHEMBL3930766 | 0.79 | MTNR1A (0.52) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A | |
| SCHEMBL3930770 | 0.79 | MTNR1A (0.52) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A | |
| SCHEMBL3928924 | 0.78 | MTNR1A (0.51) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A | |
| SCHEMBL3928926 | 0.78 | MTNR1A (0.51) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A | |
| SCHEMBL11168474 | 0.76 | HTR1B (0.66) | HTR2ACYP2D6MAOAMAOB | |
| SCHEMBL10985197 | 0.76 | HTR1B (0.66) | HTR2ACYP2D6MAOAMAOB | |
| SCHEMBL3929104 | 0.74 | CYP2D6 (0.50) | MTNR1ACYP2D6MTNR1BADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536503-A | Naphthoxyalkylamines and related compounds as antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-20 | — | — | US | disclosed |