Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 3/20 | 0.50 |
| ▸ | OTC | P00480 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medronic Acid SCHEMBL10976068 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL1424027 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL10982969 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Diaminooctane SCHEMBL10974775 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL180702 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL5159603 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL6664306 | 1.00 | THRB (0.59) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL6363918 | 0.97 | THRB (0.56) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL6837061 | 0.97 | THRB (0.56) | THRBKDM4EMMP2MAPK1HSD17B10 | |
| Medronic Acid SCHEMBL2946849 | 0.97 | THRB (0.56) | THRBKDM4EMMP2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038183-B1 | POLYPHENYLENE ETHER RESIN COMPOSITIONS AND SHAPED ARTICLES THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-07-31 | — | — | EP | disclosed |
| US-4383066-A | Polyphenylene ether resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0038183-A1 | Polyphenylene ether resin compositions and shaped articles thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-10-21 | — | — | EP | disclosed |