Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545805 | 0.90 | CA1 (0.46) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7033458 | 0.90 | NR4A2 (0.48) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL744628 | 0.90 | CA1 (0.46) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7034611 | 0.88 | CA1 (0.45) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7027844 | 0.88 | CA1 (0.49) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7025204 | 0.88 | HSD17B10 (0.48) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7031182 | 0.87 | ALDH1A1 (0.45) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7027277 | 0.85 | TSHR (0.50) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL9523311 | 0.84 | CA1 (0.42) | CA1CA2CA9CA5ATSHR | |
| SCHEMBL7027862 | 0.84 | CA1 (0.42) | CA1CA2CA9CA5ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546179-A | Process for preparing sulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-10-08 | — | — | US | disclosed |
| US-4302241-A | N-(PYRIMIDIN-2-YL-AMINOCARBONYL) ARYL SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-24 | — | — | US | disclosed |