SCHEMBL744628

SCHEMBL744628

COC(=O)c1cccc(C)c1S(=O)(=O)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
NR4A2 P43354 1/20 0.45
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43
ALDH1A1 P00352 3/20 0.43
CFTR P13569 1/20 0.43
HSD17B10 Q99714 1/20 0.43
POLB P06746 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.42
ATM Q13315 1/20 0.42
PTPRC P08575 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MYC P01106 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30545805 1.00 CA1 (0.46) CA1CA2CA5ACA9NR4A2
SCHEMBL10986337 0.90 CA1 (0.51) CA1CA2CA5ACA9LMNA
SCHEMBL28302569 0.87 ALDH1A1 (0.39) CA1CA2CA5ACA9NR4A2
SCHEMBL27544203 0.85 CA1 (0.47) CA1CA2CA5ACA9NR4A2
SCHEMBL12724024 0.85 KMT2A (0.47) CA1CA2CA5ACA9NR4A2
SCHEMBL7032629 0.84 TSHR (0.56) CA1CA2CA9LMNATSHR
SCHEMBL7025312 0.83 CA1 (0.58) CA1CA2CA5ACA9NR4A2
SCHEMBL7033458 0.83 NR4A2 (0.48) CA1CA2CA5ACA9NR4A2
SCHEMBL7033378 0.83 NPC1 (0.49) CA1CA2CA9LMNAALDH1A1
SCHEMBL7034611 0.82 CA1 (0.45) CA1CA2CA5ACA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116554063-B Preparation method of flusulfamuron intermediate 江苏省农用激素工程技术研究中心有限公司 2025-03-07 CN claimed
CN-116554063-A Preparation method of flusulfamuron intermediate 江苏省农用激素工程技术研究中心有限公司 2023-08-08 CN claimed
CN-112979506-B Synthesis method of 2-chlorosulfonyl-3-methyl benzoate 南京合创药业有限公司 2021-08-24 CN claimed
CN-112979506-A Synthesis method of 2-chlorosulfonyl-3-methyl benzoate 南京合创药业有限公司 2021-06-18 CN claimed
CN-212395960-U Demulsification device used in production of 2-chlorosulfonyl-3-methyl benzoate 南京合创药业有限公司 2021-01-26 CN claimed
CN-116554063-B Preparation method of flusulfamuron intermediate 江苏省农用激素工程技术研究中心有限公司 2025-03-07 CN disclosed
CN-116554063-B Preparation method of flusulfamuron intermediate 江苏省农用激素工程技术研究中心有限公司 2025-03-07 CN disclosed
CN-116554063-A Preparation method of flusulfamuron intermediate 江苏省农用激素工程技术研究中心有限公司 2023-08-08 CN disclosed
CN-116554063-A Preparation method of flusulfamuron intermediate 江苏省农用激素工程技术研究中心有限公司 2023-08-08 CN disclosed
CN-112979506-A Synthesis method of 2-chlorosulfonyl-3-methyl benzoate 南京合创药业有限公司 2021-06-18 CN disclosed
EP-2430023-B1 AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS HOFFMANN LA ROCHE (CH) 2013-12-11 EP disclosed
US-8329904-B2 Azacyclic derivatives HOFFMANN-LA ROCHE INC. (US) 2012-12-11 US disclosed
US-5550238-A Process for preparing sulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-27 US disclosed
EP-0336587-B1 FLUOROALKOXY AMINO TRIAZINES FOR CONTROL OF WEEDS IN SUGAR BEETS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-11 EP disclosed
EP-0537585-A2 Process for preparing sulfonylureas E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-21 EP disclosed
US-5157119-A Process for preparing sulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-20 US disclosed
US-5090993-A Herbicides, plant growth regulators E. I. DU PONT DE NEMOURS & COMPANY (US) 1992-02-25 US disclosed
EP-0406322-A1 FLUOROALKOXY AMINO TRIAZINES FOR CONTROL OF WEEDS IN SUGAR BEETS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-09 EP disclosed
EP-0336587-A1 Fluoroalkoxy amino triazines for control of weeds in sugar beets E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-11 EP disclosed
WO-1989009214-A1 FLUOROALKOXY AMINO TRIAZINES FOR CONTROL OF WEEDS IN SUGAR BEETS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-05 WO disclosed