Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981812 | 0.84 | MEN1 (0.59) | MEN1KMT2AALDH1A1POLBNPSR1 | |
| SCHEMBL10984399 | 0.83 | LMNA (0.58) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL10986970 | 0.79 | KMT2A (0.55) | MEN1KMT2AALDH1A1POLBKCNH2 | |
| Hydrochloric Acid SCHEMBL7265511 | 0.78 | KMT2A (0.54) | MEN1KMT2AALDH1A1POLBKCNH2 | |
| SCHEMBL13627523 | 0.74 | KMT2A (0.54) | MEN1KMT2AALDH1A1KCNH2MAOB | |
| SCHEMBL3674806 | 0.74 | MAOB (0.62) | MEN1KMT2ALMNAMAOB | |
| SCHEMBL10986157 | 0.73 | KMT2A (0.71) | MEN1KMT2APOLBNPSR1LMNA | |
| SCHEMBL7271600 | 0.73 | KMT2A (0.54) | MEN1KMT2AALDH1A1POLBKCNH2 | |
| SCHEMBL4473413 | 0.72 | MAOB (0.61) | MEN1KMT2ALMNAMAOB | |
| SCHEMBL28256912 | 0.72 | MAOB (0.65) | MEN1KMT2AALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528194-A | 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, a process for their production and a cerebral circulation-improving drug | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |