Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786926 | 0.85 | HNF4A (0.92) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL29662951 | 0.85 | HNF4A (1.00) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL73041 | 0.85 | HNF4A (1.00) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL496623 | 0.83 | SLC6A4 (0.64) | HNF4ASLC6A4SLC6A3CYP3A4NR4A1 | |
| Hydrochloric Acid SCHEMBL27574420 | 0.83 | HNF4A (0.96) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| Bicarbonate SCHEMBL236888 | 0.83 | HNF4A (0.96) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL5964729 | 0.83 | HNF4A (0.96) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL28302531 | 0.83 | HNF4A (0.96) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL410536 | 0.83 | HNF4A (0.96) | HNF4AALDH1A1HSD17B10KDM4EAKR1C3 | |
| SCHEMBL942728 | 0.81 | HNF4A (0.67) | HNF4ADHODHALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4513052-A | LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND | RICOH CO., LTD. (JP) | 1985-04-23 | — | — | US | claimed |
| WO-2016086071-A1 | SPECTRALLY ENCODED CONSUMABLE SPECTROMETER APPARATUS AND METHODS | NUEOU, INC. (US) | 2016-06-02 | — | — | WO | disclosed |