SCHEMBL10987178

SCHEMBL10987178

CCCCCCC(I)C#CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.46
FFAR1 O14842 2/20 0.46
MAPT P10636 1/20 0.44
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
FFAR4 Q5NUL3 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
CA2 P00918 1/20 0.39
HMGCR P04035 1/20 0.39
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8985101 0.81 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL29211086 0.81 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8971531 0.81 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8971535 0.81 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL272762 0.81 ACE2 (0.44) GPR84FFAR1MAPTLCKPPARD
SCHEMBL29211102 0.81 GPR84 (0.53) GPR84FFAR1MAPTLCKPPARD
SCHEMBL29211129 0.79 GPR84 (0.50) GPR84FFAR1MAPTLCKPPARD
SCHEMBL29410214 0.76 GRIK1 (0.44) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8847097 0.74 ACE2 (0.42) GPR84FFAR1MAPTLCKPPARD
SCHEMBL10541046 0.74 LMNA (0.38) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0032622-B1 POLYMERISABLE PHOSPHOLIPIDS AND POLYMERS THEREOF, METHODS FOR THEIR PREPARATION, METHODS FOR THEIR USE IN COATING SUBSTRATES AND FORMING LIPOSOMES AND THE RESULTING COATED SUBSTRATES AND LIPOSOME COMPOSITIONS Chapman, Dennis (GB) 1985-08-14 EP disclosed
US-4348329-A PHOSPHOLIPIDS HAVING CONJUGATED DI-YNE SYSTEM AVANTI POLAR LIPIDS, INC. 1982-09-07 US disclosed
EP-0032622-A1 Polymerisable phospholipids and polymers thereof, methods for their preparation, methods for their use in coating substrates and forming liposomes and the resulting coated substrates and liposome compositions Chapman, Dennis (GB) 1981-07-29 EP disclosed