Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510257 | 1.00 | MAPT (0.71) | MAPTALDH1A1HPGDNPC1CRHBP | |
| SCHEMBL11536521 | 0.94 | HPGD (0.73) | MAPTALDH1A1HPGDNPC1CRHBP | |
| SCHEMBL11408843 | 0.91 | MAPT (0.83) | MAPTALDH1A1HPGDCYP19A1KDM4E | |
| SCHEMBL9977912 | 0.88 | CYP19A1 (0.70) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10557875 | 0.86 | MAPT (0.75) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11608031 | 0.86 | MAPT (0.75) | MAPTALDH1A1HPGDCYP19A1KDM4E | |
| SCHEMBL626949 | 0.84 | MAPT (0.73) | MAPTALDH1A1HPGDCYP19A1KDM4E | |
| SCHEMBL13298096 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDNPC1CRHBP | |
| SCHEMBL28965383 | 0.83 | MAPT (0.66) | MAPTALDH1A1CYP19A1LMNAPOLB | |
| SCHEMBL8162593 | 0.83 | MAPT (0.71) | MAPTALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018743-A | Process for preparing triketoimidazolidines | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | claimed |
| US-4497915-A | Molding compositions containing triketoimidazolidine precondensates, their use, and a process for preparing a triketoimidazolidine precondensate composite suitable for this purpose | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-05 | — | — | US | disclosed |
| US-4483947-A | Molding compositions containing triketoimidazolidine precondensates, their use, and a process for preparing a triketoimidazolidine precondensate composite suitable for this purpose | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-20 | — | — | US | disclosed |