Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983146 | 0.87 | KDM4E (0.42) | MAPTNPC1RAB9AFFAR1BRD4 | |
| SCHEMBL10989963 | 0.84 | CYP1A1 (0.47) | CYP1A1MAPTBRD4ATP4AATP4B | |
| SCHEMBL10977613 | 0.84 | KDM4E (0.49) | MAPTNPC1RAB9ABRD4BRD2 | |
| SCHEMBL10831999 | 0.83 | AURKB (0.43) | MAPTNPC1RAB9ABRD4BRD2 | |
| SCHEMBL10984243 | 0.80 | CYP1A1 (0.43) | CYP1A1MAPTFFAR1PPARGBRD4 | |
| SCHEMBL10832143 | 0.78 | PTGS2 (0.51) | CYP1A1MAPTNPC1RAB9ABRD4 | |
| SCHEMBL10986778 | 0.73 | KDM4E (0.45) | MAPTNPC1RAB9ABRD4TTK | |
| SCHEMBL2731040 | 0.71 | CYP1A1 (0.48) | CYP1A1MAPTFFAR1PPARGATP4A | |
| SCHEMBL2730780 | 0.71 | CYP1A1 (0.48) | CYP1A1MAPT | |
| SCHEMBL11079151 | 0.71 | NPC1 (0.40) | NPC1RAB9ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499279-A | ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4467096-A | ANTIDIABETIC AGENTS, INTERMEDIATES THEREFOR | SANDOZ, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4421752-A | ANTIDIABETIC AGENT | SANDOZ, INC. (US) | 1983-12-20 | — | — | US | disclosed |
| US-4419353-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1983-12-06 | — | — | US | disclosed |
| US-4397850-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4336391-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4336379-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |