Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10982831 | 0.90 | MGAM (0.35) | GAAMGAMSIMGAM2CYP19A1 | |
| SCHEMBL7740543 | 0.85 | GAA (0.50) | GAAMGAMSIMGAM2NAAA | |
| SCHEMBL11293843 | 0.85 | GAA (0.50) | GAAMGAMSIMGAM2NAAA | |
| SCHEMBL10620127 | 0.80 | DPP4 (0.36) | DPP4DPP8DPP9 | |
| SCHEMBL11404161 | 0.78 | NAAA (0.36) | NAAACYP19A1HTTEPHX1APOBEC3A | |
| SCHEMBL1319964 | 0.77 | NAAA (0.47) | GAAMGAMSIMGAM2NAAA | |
| SCHEMBL2005549 | 0.77 | NAAA (0.52) | GAAMGAMSIMGAM2NAAA | |
| SCHEMBL7636739 | 0.76 | EPHX1 (0.53) | GAAMGAMSIMGAM2NAAA | |
| SCHEMBL11410127 | 0.76 | NAAA (0.44) | GAANAAACYP19A1SMN1; SMN2MAPT | |
| SCHEMBL11410395 | 0.75 | DPP4 (0.36) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |