Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620127 | 0.94 | DPP4 (0.36) | DPP4DPP8DPP9CHRM2CHRM1 | |
| SCHEMBL25500893 | 0.84 | CHRM2 (0.42) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL11414635 | 0.81 | CYP19A1 (0.31) | — | |
| SCHEMBL11410110 | 0.81 | CYP19A1 (0.31) | — | |
| SCHEMBL11404161 | 0.81 | NAAA (0.36) | CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL11410127 | 0.78 | NAAA (0.44) | — | |
| SCHEMBL15692146 | 0.77 | GRM1 (0.32) | — | |
| SCHEMBL12476221 | 0.77 | CHRM2 (0.42) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL177205 | 0.77 | — | — | |
| SCHEMBL21872695 | 0.76 | CHRM2 (0.42) | DPP4DPP8DPP9CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181625-A | CARBONITRILES, DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-01-01 | — | — | US | claimed |
| US-4181625-A | CARBONITRILES, DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-01-01 | — | — | US | disclosed |