Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988156 | 1.00 | MAPT (0.49) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL10986371 | 0.82 | NAMPT (0.49) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL10986373 | 0.82 | NAMPT (0.49) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL10984253 | 0.80 | AKR1C3 (0.52) | MAPTSMN1; SMN2KMT2AALDH1A1TDP1 | |
| SCHEMBL10984250 | 0.80 | AKR1C3 (0.52) | MAPTSMN1; SMN2KMT2AALDH1A1TDP1 | |
| SCHEMBL1583517 | 0.78 | MAPT (0.55) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL7127950 | 0.78 | MAPT (0.55) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL8039279 | 0.78 | MAPT (0.59) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL13678892 | 0.74 | MAPT (0.51) | MAPTSMN1; SMN2LMNAMAPK1KDM4E | |
| SCHEMBL6856019 | 0.74 | MAPT (0.55) | MAPTSMN1; SMN2LMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |