Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984250 | 1.00 | AKR1C3 (0.52) | AKR1C3RECQLFBP1ALDH1A1TSHR | |
| SCHEMBL28418953 | 0.81 | FBP1 (0.49) | AKR1C3RECQLFBP1ALDH1A1TSHR | |
| SCHEMBL11564387 | 0.81 | AKR1C3 (0.48) | AKR1C3RECQLFBP1ALDH1A1TSHR | |
| SCHEMBL11564392 | 0.81 | AKR1C3 (0.48) | AKR1C3RECQLFBP1ALDH1A1TSHR | |
| SCHEMBL10988156 | 0.80 | MAPT (0.49) | ALDH1A1PTGS2TDP1MEN1KMT2A | |
| SCHEMBL10988151 | 0.80 | MAPT (0.49) | ALDH1A1PTGS2TDP1MEN1KMT2A | |
| SCHEMBL10989710 | 0.77 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11114396 | 0.77 | MAPT (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10986015 | 0.77 | ALDH1A1 (0.42) | AKR1C3ALDH1A1TSHRHTTTDP1 | |
| SCHEMBL10986325 | 0.75 | CA1 (0.47) | ALDH1A1PTGS2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110730781-B | Tetrahydropyridopyrazine modulators of GPR6 | 武田药品工业株式会社 | 2023-05-05 | — | — | CN | claimed |
| CN-110730781-B | Tetrahydropyridopyrazine modulators of GPR6 | 武田药品工业株式会社 | 2023-05-05 | — | — | CN | disclosed |
| US-4551467-A | Vasodilating cyanoalkyl esters of 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |