Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10990634 | 1.00 | MAPT (0.46) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL10985936 | 0.82 | MAPT (0.53) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL10996793 | 0.80 | MAPT (0.33) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL10987773 | 0.77 | MEN1 (0.41) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL9829808 | 0.75 | RAB9A (0.58) | MAPTHTTKMT2AMEN1GSTO1 | |
| SCHEMBL9832583 | 0.74 | LMNA (0.57) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL4318524 | 0.72 | GAA (0.43) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL9595515 | 0.70 | MAPT (0.48) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL11034895 | 0.70 | MAPT (0.50) | MAPTSMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL10993495 | 0.70 | GAA (0.32) | MAPTKMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491587-A | ANTIALLERGENS, ANTIHISTAMINES, MUSCLE RELAXANTS/ INSULATING POWDER BLANKET ABOVD THE MELT WITH HEAT GENERATED IN THE MELT BY ELECTRIC CURRENT; LOWER TEMPERATURE | MEAD JOHNSON & COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4223031-A | ANTIALLERGENS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, HYPERSENSITIVITY | MEAD JOHNSON & COMPANY (US) | 1980-09-16 | — | — | US | disclosed |