Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983358 | 0.99 | NPSR1 (0.65) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10986478 | 0.86 | LMNA (0.55) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10985877 | 0.85 | NPSR1 (0.57) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10838011 | 0.84 | LMNA (0.62) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| Ofornine SCHEMBL30560632 | 0.84 | LMNA (0.62) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| Ofornine SCHEMBL120272 | 0.84 | LMNA (0.62) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL7849622 | 0.84 | NPSR1 (0.62) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10838059 | 0.84 | LMNA (0.62) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10987338 | 0.84 | NPSR1 (0.52) | NPSR1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10980204 | 0.84 | SMN1; SMN2 (0.74) | NPSR1LMNAKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | claimed |
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |