Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677598 | 0.84 | CNR2 (0.63) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8875796 | 0.82 | LMNA (0.68) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3003247 | 0.78 | POLB (0.62) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8643272 | 0.77 | LMNA (0.62) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3246579 | 0.77 | LMNA (0.63) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| Morpholine SCHEMBL10990896 | 0.74 | LMNA (0.80) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3248500 | 0.74 | LMNA (0.74) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL1322507 | 0.73 | LMNA (1.00) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL2008020 | 0.73 | PLA2G2A (0.69) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL11190363 | 0.72 | PLA2G2A (0.63) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551475-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |