Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986888 | 0.93 | POLB (0.55) | RAB9ALMNAPOLBNPC1HTT | |
| SCHEMBL10995111 | 0.91 | LMNA (0.50) | RAB9ALMNAPOLBGAAHTT | |
| SCHEMBL10986641 | 0.91 | POLB (0.54) | RAB9ALMNAPOLBL3MBTL1GAA | |
| SCHEMBL10991244 | 0.91 | POLB (0.54) | RAB9ALMNAPOLBL3MBTL1KCNA5 | |
| SCHEMBL10989692 | 0.91 | ALDH1A1 (0.56) | RAB9APOLBNPC1L3MBTL1KCNA5 | |
| SCHEMBL10995044 | 0.91 | ALDH1A1 (0.48) | RAB9ALMNAPOLBKCNA5GAA | |
| SCHEMBL11000010 | 0.91 | POLB (0.52) | RAB9ALMNAPOLBNPC1L3MBTL1 | |
| SCHEMBL10996385 | 0.90 | POLB (0.51) | RAB9ALMNAPOLBNPC1L3MBTL1 | |
| SCHEMBL10994793 | 0.89 | POLB (0.50) | RAB9ALMNAPOLBNPC1L3MBTL1 | |
| SCHEMBL10994260 | 0.89 | POLB (0.50) | RAB9ALMNAPOLBNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | claimed |
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |