Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MECP2 | P51608 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996108 | 0.79 | PARP1 (0.69) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8888959 | 0.76 | PARP1 (0.55) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL2347376 | 0.74 | NPC1 (0.62) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL30398025 | 0.73 | NPC1 (0.61) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL17174132 | 0.73 | NPC1 (0.58) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL12880844 | 0.71 | PARP1 (0.65) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL30289774 | 0.71 | NPC1 (0.59) | PARP1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29911013 | 0.71 | POLB (0.62) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL17552175 | 0.71 | POLB (0.62) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL7616828 | 0.70 | IKBKB (0.52) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530931-A | 8-Quinoline carbanilates for the inhibition of lipolysis | USV PHARMACEUTICAL CORP. (US) | 1985-07-23 | — | — | US | disclosed |