Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14329875 | 0.87 | NPC1 (0.58) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17174132 | 0.87 | NPC1 (0.58) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11369248 | 0.82 | PARP1 (0.52) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12112562 | 0.82 | PARP1 (0.44) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17955215 | 0.80 | NPC1 (0.50) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11962281 | 0.79 | TEAD4 (0.44) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3628069 | 0.78 | NPC1 (0.61) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL707767 | 0.77 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4486496 | 0.77 | KDM4E (0.70) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11962278 | 0.77 | RAB9A (0.54) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363643-A1 | Pesticides based on partially different 2-aryl-substituted 1-10-phenanthrolines, and their preparation | BAYER AG (DE) | 1990-04-18 | — | — | EP | claimed |
| CN-110803971-B | Method for preparing bibenzyl compound through photocatalysis | 南方科技大学 | 2022-10-28 | — | — | CN | disclosed |
| US-20220119435-A1 | COMPOSITIONS OF MECHANICALLY INTERLOCKED, TOPOLOGICALLY COMPLEX CROSSLINKERS AND POLYMERS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2022-04-21 | — | — | US | disclosed |
| US-8669335-B2 | Knotty polymers via supramolecularly templated macroinitiators and living polymerization and methods for making and using same | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2014-03-11 | — | — | US | disclosed |
| US-8071975-B2 | Electronic devices made with electron transport and/or anti-quenching layers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110207878-A1 | KNOTTY POLYMERS VIA SUPRAMOLECULARLY TEMPLATED MACROINITIATORS AND LIVING POLYMERIZATION AND METHODS FOR MAKING AND USING SAME | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2011-08-25 | — | — | US | disclosed |
| WO-2011100757-A2 | KNOTTY POLYMERS VIA SUPRAMOLECULARLY TEMPLATED MACROINITIATORS AND LIVING POLYMERIZATION AND METHODS FOR MAKING AND USING SAME | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2011-08-18 | — | — | WO | disclosed |
| US-20090121617-A1 | ELECTRONIC DEVICES MADE WITH ELECTRON TRANSPORT AND/OR ANTI-QUENCHING LAYERS | LG CHEM, LTD. (KR) | 2009-05-14 | — | — | US | disclosed |
| US-20070267968-A1 | ELECTRONIC DEVICES MADE WITH ELECTRON TRANSPORT AND/OR ANTI-QUENCHING LAYERS | LECLOUX DANIEL D | 2007-11-22 | — | — | US | disclosed |
| US-7265378-B2 | Electronic devices made with electron transport and/or anti-quenching layers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-04 | — | — | US | disclosed |
| EP-0363643-A1 | Pesticides based on partially different 2-aryl-substituted 1-10-phenanthrolines, and their preparation | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119435-A1 | COMPOSITIONS OF MECHANICALLY INTERLOCKED, TOPOLOGICALLY COMPLEX CROSSLINKERS AND POLYMERS AND METHODS OF MAKING AND USING SAME | PCNA, SMC4, ERCC5 | NPC1 4657/4885RAB9A 4102/4885ALDH1A1 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.