Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923027 | 0.75 | ALDH1A1 (0.53) | L3MBTL1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL1195573 | 0.74 | SCN8A (0.51) | L3MBTL1GAASCN2ASCN8AALDH1A1 | |
| SCHEMBL21601421 | 0.73 | L3MBTL1 (0.61) | L3MBTL1SCN2ASCN8AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1194515 | 0.73 | SCN8A (0.50) | L3MBTL1GAASCN2ASCN8AALDH1A1 | |
| SCHEMBL15346333 | 0.71 | ALDH1A1 (0.52) | L3MBTL1GAASCN2ASCN8AALDH1A1 | |
| SCHEMBL21595893 | 0.71 | L3MBTL1 (0.67) | L3MBTL1SCN8AALDH1A1MAPTATM | |
| Hydrochloric Acid SCHEMBL1194796 | 0.70 | ALDH1A1 (0.51) | L3MBTL1GAASCN2ASCN8AALDH1A1 | |
| SCHEMBL1195811 | 0.70 | KDM4E (0.54) | SCN2ASCN8AALDH1A1KDM4ECYP2D6 | |
| Fumaric Acid SCHEMBL10992174 | 0.69 | SCN8A (0.53) | L3MBTL1SCN8AALDH1A1MAPTATM | |
| Maleic Acid SCHEMBL10992168 | 0.69 | SCN8A (0.53) | L3MBTL1SCN8AALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558155-A | N-(Aryloxyalkyl)-N'-(aminoalkyl)thioureas | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-10 | — | — | US | disclosed |
| US-4500529-A | ANTIARRHYTHMIA AGENT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-02-19 | — | — | US | disclosed |