Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765908 | 0.85 | TTR (0.54) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL11352725 | 0.85 | TTR (0.54) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL16581127 | 0.85 | TTR (0.54) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL3875921 | 0.85 | TTR (0.54) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL1222307 | 0.82 | TTR (0.78) | TTRNPC1RAB9ALMNABCAT1 | |
| Furobufen SCHEMBL43450 | 0.82 | CYP1A2 (0.58) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL11599094 | 0.82 | NPC1 (0.57) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL8912973 | 0.82 | TTR (0.51) | TTRNPC1RAB9ALMNABCAT1 | |
| Furobufen SCHEMBL30901203 | 0.82 | CYP1A2 (0.58) | TTRNPC1RAB9ALMNABCAT1 | |
| SCHEMBL23626600 | 0.81 | TTR (0.50) | TTRNPC1RAB9ALMNABCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |