Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765635 | 0.83 | NPC1 (0.79) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL1283826 | 0.83 | NPC1 (0.79) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL10992173 | 0.82 | TTR (0.55) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL16581127 | 0.81 | TTR (0.54) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL30765908 | 0.81 | TTR (0.54) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL26304440 | 0.81 | NPC1 (0.74) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL11352725 | 0.81 | TTR (0.54) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL3875921 | 0.81 | TTR (0.54) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL14497165 | 0.81 | PLOD2 (0.50) | NPC1RAB9ATTRBCAT1LMNA | |
| SCHEMBL11843702 | 0.80 | KDM4E (0.60) | NPC1RAB9ATTRBCAT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082807-A | REACTING AN AROMATIC COMPOUND WITH AN ACETOACETYL FLUORIDE; HYDROGEN FLUORIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |
| US-3937737-A | CHEMICAL INTERMEDIATES, DYES, PLASTICS, METAL COMPLEXES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |