Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083446 | 0.80 | MAPT (0.47) | MAPTCYP1A2CYP2C19CYP3A4SLC6A4 | |
| Dimethyl Phthalate SCHEMBL10886419 | 0.78 | TSHR (0.45) | MAPTSLC6A4TSHRSLC6A2HSD17B10 | |
| SCHEMBL2047496 | 0.71 | MAPT (0.45) | MAPTCYP1A2CYP2C19CYP3A4SLC6A4 | |
| Indene SCHEMBL28869263 | 0.70 | CYP2D6 (0.49) | CYP2C19CYP2D6SMN1; SMN2CA1CA2 | |
| SCHEMBL7828978 | 0.69 | SLC6A4 (0.49) | MAPTCYP1A2CYP3A4SLC6A4TSHR | |
| SCHEMBL8096843 | 0.69 | SLC6A4 (0.49) | MAPTCYP1A2CYP3A4SLC6A4TSHR | |
| SCHEMBL8096846 | 0.69 | SLC6A4 (0.49) | MAPTCYP1A2CYP3A4SLC6A4TSHR | |
| Indene SCHEMBL6268710 | 0.69 | CYP2D6 (0.39) | CYP2C19TSHRCYP2D6HSD17B10MAPK1 | |
| Indene SCHEMBL89373 | 0.69 | CYP2D6 (0.51) | CYP2C19CYP2D6HSD17B10CA1CA2 | |
| Indene SCHEMBL29746662 | 0.69 | CYP2D6 (0.51) | CYP2C19CYP2D6HSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147593-A2 | Process for the preparation of mono- or bis-carbonyl compounds | Chemie Linz Gesellschaft m.b.H. (AT) | 1985-07-10 | — | — | EP | disclosed |