Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677193 | 0.94 | MAPT (0.52) | SQORMAPTCYP1A1CYP1B1KMT2A | |
| SCHEMBL10991494 | 0.86 | KDM4E (0.58) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10976797 | 0.86 | KDM4E (0.58) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8675465 | 0.86 | MAPT (0.59) | MAPTCYP1A1CYP1B1KMT2ANPC1 | |
| SCHEMBL8676788 | 0.85 | MAPT (0.50) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10992874 | 0.84 | ACHE (0.49) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10988231 | 0.84 | KMT2A (0.48) | MAPTCYP1A1CYP1B1KMT2ANPC1 | |
| SCHEMBL10988161 | 0.84 | PIK3CA (0.50) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5359428 | 0.84 | NPC1 (0.59) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10992758 | 0.84 | ACP1 (0.46) | KMT2ANPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533666-A | ANALGESICS, ANTIPYRETICS | ELI LILLY AND COMPANY (US) | 1985-08-06 | — | — | US | claimed |
| EP-0130044-A1 | Pyridine derivatives | ELI LILLY AND COMPANY (US) | 1985-01-02 | — | — | EP | claimed |
| US-4533666-A | ANALGESICS, ANTIPYRETICS | ELI LILLY AND COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0130044-A1 | Pyridine derivatives | ELI LILLY AND COMPANY (US) | 1985-01-02 | — | — | EP | disclosed |