Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675465 | 0.86 | MAPT (0.59) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10991494 | 0.86 | KDM4E (0.58) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10976797 | 0.86 | KDM4E (0.58) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10993183 | 0.84 | SQOR (0.53) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5359428 | 0.84 | NPC1 (0.59) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10992874 | 0.84 | ACHE (0.49) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10988161 | 0.84 | PIK3CA (0.50) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10992758 | 0.81 | ACP1 (0.46) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL8680387 | 0.81 | MAPT (0.56) | KMT2AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL8677193 | 0.80 | MAPT (0.52) | KMT2AKDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0130044-A1 | Pyridine derivatives | ELI LILLY AND COMPANY (US) | 1985-01-02 | — | — | EP | claimed |
| US-4533666-A | ANALGESICS, ANTIPYRETICS | ELI LILLY AND COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0130044-A1 | Pyridine derivatives | ELI LILLY AND COMPANY (US) | 1985-01-02 | — | — | EP | disclosed |