Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | USP4 | Q13107 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508139 | 0.87 | USP8 (0.42) | USP8USP2USP5USP4USP7 | |
| SCHEMBL11000333 | 0.80 | KDM4E (0.40) | USP8 | |
| SCHEMBL9356027 | 0.79 | USP8 (0.41) | USP8USP2USP5USP4USP7 | |
| SCHEMBL507982 | 0.79 | USP8 (0.44) | USP8USP2USP5USP4USP7 | |
| SCHEMBL20036425 | 0.72 | USP8 (0.40) | USP8USP2USP5USP4USP7 | |
| SCHEMBL3607648 | 0.71 | KDM4E (0.44) | USP8USP2USP5USP4USP7 | |
| SCHEMBL8200210 | 0.71 | ALDH1A1 (0.45) | USP8 | |
| SCHEMBL12682521 | 0.71 | PLAU (0.38) | USP8USP2USP5USP4USP7 | |
| Water SCHEMBL11498438 | 0.71 | USP8 (0.37) | USP8USP2USP5USP4USP7 | |
| SCHEMBL24263905 | 0.70 | USP8 (0.39) | USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517186-A | BACTERICIDES, FUNGICIDES | MERCK & CO., INC. (US) | 1985-05-14 | — | — | US | disclosed |