Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | USP4 | Q13107 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356027 | 0.94 | USP8 (0.41) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL508139 | 0.90 | USP8 (0.42) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL137039 | 0.87 | USP8 (0.35) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL29437694 | 0.87 | USP8 (0.35) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL20036425 | 0.85 | USP8 (0.40) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL21074155 | 0.84 | USP8 (0.37) | USP8HTT | |
| SCHEMBL24263905 | 0.83 | USP8 (0.39) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL20651248 | 0.83 | USP8 (0.39) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL19484668 | 0.83 | USP8 (0.39) | USP8KDM4EALDH1A1CSNK1A1CLK4 | |
| SCHEMBL9883299 | 0.83 | USP8 (0.39) | USP8KDM4EALDH1A1CSNK1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995589-B | Process for producing 2, 5-dicyano-3, 6-dihalopyrazine | 国立大学法人九州大学 | 2023-12-05 | — | — | CN | claimed |
| EP-3882236-B1 | PRODUCTION METHOD FOR 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | UNIV KYUSHU NAT UNIV CORP (JP) | 2023-01-11 | — | — | EP | claimed |
| EP-3882236-A1 | PRODUCTION METHOD FOR 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | Kyushu University National University Corporation (JP) | 2021-09-22 | — | — | EP | claimed |
| CN-111995589-A | Process for producing 2, 5-dicyano-3, 6-dihalopyrazine | 国立大学法人九州大学 | 2020-11-27 | — | — | CN | claimed |
| US-20190169170-A1 | DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL, LUMINESCENCE DEVICE USING THE SAME, AND METHOD FOR PRODUCING 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| US-20180273513-A1 | DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL, LUMINESCENCE DEVICE USING THE SAME, AND METHOD FOR PRODUCING 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-09-27 | — | — | US | claimed |
| EP-3375779-A1 | DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL, LIGHT TRANSMITTER USING SAME, AND PRODUCTION METHOD FOR 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | Kyushu University National University Corporation (JP) | 2018-09-19 | — | — | EP | claimed |
| CN-108137554-A | Dicyanopyrazine compound, light-emitting material, light-emitting element using the light-emitting material, and method for producing 2, 5-dicyano-3, 6-dihalopyrazine | 国立大学法人九州大学 | 2018-06-08 | — | — | CN | claimed |
| US-8778224-B2 | Fluorescent dye-siloxane hybrid resin | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-15 | — | — | US | claimed |
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2010-05-06 | — | — | US | claimed |
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | MALLINCKRODT INC. (US) | 2008-12-04 | — | — | US | claimed |
| EP-1793866-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT, INC. (US) | 2007-06-13 | — | — | EP | claimed |
| WO-2006026038-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2006-03-09 | — | — | WO | claimed |
| EP-0441976-B1 | 3,6-DIAMINO-2,5-PYRAZINEDICARBONITRILE AND PRODUCTION THEREOF | NIPPON SODA CO (JP) | 1994-11-17 | — | — | EP | claimed |
| US-5317102-A | MANUFACTURED FROM THIO-SUBSTITUTED 2,3-DIAMINOACRYLONITRILE COMPOUNDS | NIPPON SODA CO., LTD. (JP) | 1994-05-31 | — | — | US | claimed |
| US-5294711-A | 3,6-diamino-2,5-pyrazinedicarbonitrile | NIPPON SODA CO., LTD. (JP) | 1994-03-15 | — | — | US | claimed |
| EP-0441976-A1 | 3,6-DIAMINO-2,5-PYRAZINEDICARBONITRILE AND PRODUCTION THEREOF | NIPPON SODA CO., LTD. (JP) | 1991-08-21 | — | — | EP | claimed |
| JP-5059016-A | — | — | None | — | — | JP | disclosed |
| EP-0441976-A1 | 3,6-DIAMINO-2,5-PYRAZINEDICARBONITRILE AND PRODUCTION THEREOF | NIPPON SODA CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| WO-1991003469-A1 | 3,6-DIAMINO-2,5-PYRAZINEDICARBONITRILE AND PRODUCTION THEREOF | NIPPON SODA CO., LTD. (JP) | 1991-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299038-A1 | Luminescent Metal Complexes for Monitoring Renal Function | REN, GLS, ATP6V1B1 | USP8 4707/4885KDM4E 3283/4885ALDH1A1 1246/4885 |
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | REN, GLS, ATP6V1B1 | USP8 4665/4885KDM4E 3172/4885ALDH1A1 1388/4885 |
| US-20180273513-A1 | DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL, LUMINESCENCE DEVICE USING THE SAME, AND METHOD FOR PRODUCING 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | DDT, NDUFS5, SDHA | USP8 3710/4885KDM4E 2783/4885ALDH1A1 1085/4885 |
| US-20190169170-A1 | DICYANOPYRAZINE COMPOUND, LUMINESCENT MATERIAL, LUMINESCENCE DEVICE USING THE SAME, AND METHOD FOR PRODUCING 2,5-DICYANO-3,6-DIHALOGENOPYRAZINE | DDT, HDHD5, F3 | USP8 3574/4885KDM4E 2917/4885ALDH1A1 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.