Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | FADS1 | O60427 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988131 | 0.80 | GRM2 (0.41) | GRM2METAP2 | |
| SCHEMBL9735938 | 0.78 | AR (0.42) | GRM2DRD2DRD3KCNH2NOTUM | |
| SCHEMBL10987526 | 0.74 | TSHR (0.37) | DRD2DRD3KCNH2NOTUMMETAP2 | |
| SCHEMBL10973921 | 0.73 | NSD2 (0.47) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL16705239 | 0.71 | NSD2 (0.64) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL8196697 | 0.68 | NSD2 (0.41) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL3559706 | 0.67 | NSD2 (0.58) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL10988404 | 0.66 | GRM2 (0.39) | GRM2 | |
| SCHEMBL8103621 | 0.66 | NSD2 (0.50) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL10652687 | 0.66 | DRD2 (0.41) | GRM2DRD2DRD3KCNH2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505737-A | HALOGENATED PHENYLPYRROLIDONE AND HALOALKYLPHOSPHONIC ACID | STAUFFER CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4428767-A | A PYRROLIDONE AND A CYCLOHEXENEDIONE | STAUFFER CHEMICAL COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4416684-A | PYRROLIDONE AND M-UREIDOPHENYL CARBAMATE | STAUFFER CHEMICAL COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0015453-B1 | SYNERGISTIC HERBICIDAL COMPOSITIONS AND METHOD FOR CONTROLLING UNDESIRABLE VEGETATION | STAUFFER CHEMICAL COMPANY (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4263038-A | 3-AMINO-TRIAZOLE AND A PYRROLIDONE | STAUFFER CHEMICAL COMPANY (US) | 1981-04-21 | — | — | US | disclosed |
| EP-0015453-A2 | Synergistic herbicidal compositions and method for controlling undesirable vegetation | STAUFFER CHEMICAL COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |
| US-4210589-A | CYCLIZATION | STAUFFER CHEMICAL COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4110105-A | Aromatic N-substituted halo-substituted-2-pyrrolidinones and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-08-29 | — | — | US | disclosed |