Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 8/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491328 | 0.87 | GRM2 (0.45) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL10434289 | 0.71 | GRM2 (0.42) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL9494260 | 0.69 | GRM2 (0.43) | GRM2FADS1DRD2DRD3KCNH2 | |
| SCHEMBL10973921 | 0.69 | NSD2 (0.47) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL10993294 | 0.68 | NSD2 (0.52) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL10582421 | 0.67 | GRM2 (0.41) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL10582679 | 0.66 | GRM2 (0.40) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL16705239 | 0.66 | NSD2 (0.64) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL16789934 | 0.66 | DRD2 (0.59) | NSD2GRM2FADS1DRD2DRD3 | |
| SCHEMBL8010813 | 0.64 | ALDH1A1 (0.40) | DRD2DRD3NOTUMALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000042032-A1 | SUBSTITUTED 2-IMINO THIAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |