Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10994641 | 0.99 | HTR1A (0.52) | HTR1AADRA1DDRD2HTR2AADRA1A | |
| SCHEMBL10989155 | 0.92 | DRD2 (0.44) | HTR1AADRA1DDRD2HTR2AADRA1A | |
| SCHEMBL10991792 | 0.90 | DRD2 (0.52) | HTR1ADRD2HTR2ADRD4HTR2C | |
| SCHEMBL10992548 | 0.88 | HTR1A (0.45) | HTR1ADRD2HTR2AADRA1ADRD3 | |
| Hydrochloric Acid SCHEMBL10994952 | 0.88 | DRD2 (0.51) | HTR1ADRD2HTR2ADRD4HTR2C | |
| Hydrochloric Acid SCHEMBL10994954 | 0.88 | DRD2 (0.51) | HTR1ADRD2HTR2ADRD4HTR2C | |
| SCHEMBL10990256 | 0.86 | DRD2 (0.49) | HTR1ADRD2HTR2AADRA1ADRD3 | |
| Hydrochloric Acid SCHEMBL11551804 | 0.86 | DRD2 (0.49) | HTR1ADRD2HTR2AADRA1ADRD3 | |
| SCHEMBL10993273 | 0.85 | KCNN2 (0.44) | KDM4ELMNA | |
| SCHEMBL9131918 | 0.85 | KDM4E (0.47) | HTR1AADRA1DDRD2HTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556656-A | HYPOTENSIVE, ANTIPSYCHOTIC, DIABETIC, AND ANALGESIC AGENTS | THE UPJOHN COMPANY (US) | 1985-12-03 | — | — | US | claimed |