Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986666 | 0.90 | CYP2C19 (0.46) | CYP2C19P2RY12CYP1A2KMT2AENPP2 | |
| SCHEMBL9621580 | 0.80 | P2RY12 (0.64) | CYP2C19P2RY12CYP1A2KMT2AHSP90AA1 | |
| SCHEMBL13125431 | 0.80 | HSP90AA1 (0.57) | CYP2C19P2RY12CYP1A2KMT2AHSP90AA1 | |
| SCHEMBL10985567 | 0.77 | CYP2C19 (0.46) | CYP2C19P2RY12CYP1A2KMT2AENPP2 | |
| SCHEMBL719388 | 0.75 | CYP2C19 (0.51) | CYP2C19P2RY12CYP1A2KMT2AHSP90AA1 | |
| SCHEMBL10982599 | 0.71 | CYP2C19 (0.44) | CYP2C19P2RY12CYP1A2KMT2AENPP2 | |
| SCHEMBL9804556 | 0.69 | CYP2C19 (0.52) | CYP2C19P2RY12CYP1A2KMT2AHSP90AA1 | |
| SCHEMBL9938291 | 0.68 | P2RY12 (0.53) | CYP2C19P2RY12CYP1A2KMT2AHSP90AA1 | |
| SCHEMBL10465902 | 0.67 | CYP2C19 (0.47) | CYP2C19P2RY12CYP1A2KMT2AMEN1 | |
| SCHEMBL7035488 | 0.66 | ALPL (0.51) | CYP2C19P2RY12KMT2AMEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549019-A | Pyrimidinecarbamate derivatives as intermediates | HOFFMANN-LA ROCHE INC. (US) | 1985-10-22 | — | — | US | disclosed |