Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10605179 | 0.79 | LMNA (0.59) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL18657400 | 0.79 | LMNA (0.59) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL29733438 | 0.77 | LMNA (0.56) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL7671018 | 0.77 | LMNA (0.56) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL11143129 | 0.75 | TSHR (0.60) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL10628497 | 0.75 | TSHR (0.60) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL10756203 | 0.74 | LMNA (0.54) | LMNATSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL1219593 | 0.74 | LMNA (0.95) | LMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10991644 | 0.74 | ALDH1A1 (0.48) | LMNAATMCES2CES1GSK3B | |
| SCHEMBL8296748 | 0.74 | LMNA (0.54) | LMNATSHRMAPK1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528382-A | Imidoyl substituted pyrroles | MCNEILAB, INC. (US) | 1985-07-09 | — | — | US | disclosed |