Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988327 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARGTHRBALOX15CASP3 | |
| SCHEMBL11099548 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARGTHRBALOX15CASP3 | |
| SCHEMBL11164315 | 0.69 | CASP1 (0.37) | SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL12831619 | 0.69 | — | — | |
| SCHEMBL12831179 | 0.69 | — | — | |
| SCHEMBL12831177 | 0.69 | — | — | |
| SCHEMBL11105614 | 0.68 | SMN1; SMN2 (0.33) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL11000184 | 0.68 | SMN1; SMN2 (0.33) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL12757898 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2THRBALOX15CASP3 | |
| SCHEMBL12757887 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2THRBALOX15CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556732-A | INTERMEDIATE IN THE PRODUCTION OF ESTERS HAVING INSECTICIDAL ACTIVITY | ROUSSEL UCLAF (FR) | 1985-12-03 | — | — | US | disclosed |
| US-4500720-A | Tetrahydrofuran-2-ones | ROUSSEL UCLAF (FR) | 1985-02-19 | — | — | US | disclosed |
| EP-0057045-B1 | DERIVATIVES OF 5-HYDROXY-TETRAHYDRO-2-FURANONE | ROUSSEL-UCLAF (FR) | 1984-09-05 | — | — | EP | disclosed |
| US-4443617-A | Process for the preparation of derivatives of 6,6-dimethyl-4-hydroxy-3-oxabicyclo-[3,1,0]-hexan-2-one | ROUSSEL UCLAF (FR) | 1984-04-17 | — | — | US | disclosed |
| EP-0023849-B1 | SUBSTITUTED PENTENOIC ACID, PREPARATION THEREOF, ITS APPLICATION IN THE PREPARATION OF SUBSTITUTED CYCLOPROPANE DERIVATIVES | ROUSSEL-UCLAF (FR) | 1983-05-04 | — | — | EP | disclosed |
| EP-0057491-A2 | Halogenated derivatives of 5-hydroxy-tetrahydro-2-furanone | ROUSSEL-UCLAF (FR) | 1982-08-11 | — | — | EP | disclosed |
| EP-0057045-A2 | Derivatives of 5-hydroxy-tetrahydro-2-furanone | ROUSSEL-UCLAF (FR) | 1982-08-04 | — | — | EP | disclosed |
| EP-0023849-A2 | Substituted pentenoic acid, preparation thereof, its application in the preparation of substituted cyclopropane derivatives | ROUSSEL-UCLAF (FR) | 1981-02-11 | — | — | EP | disclosed |