Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988327 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2THRBALOX15PRKACAAKT1 | |
| SCHEMBL10994153 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2THRBALOX15PPARGCASP3 | |
| SCHEMBL11164315 | 0.68 | CASP1 (0.37) | SMN1; SMN2ALDH1A1GAACASP1CASP8 | |
| SCHEMBL2877317 | 0.67 | — | — | |
| SCHEMBL12831177 | 0.67 | — | — | |
| SCHEMBL12831619 | 0.67 | — | — | |
| SCHEMBL12831179 | 0.67 | — | — | |
| SCHEMBL13424256 | 0.66 | — | — | |
| SCHEMBL6433646 | 0.66 | — | — | |
| SCHEMBL1106080 | 0.64 | THRB (0.40) | SMN1; SMN2THRBALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057491-B1 | HALOGENATED DERIVATIVES OF 5-HYDROXY-TETRAHYDRO-2-FURANONE | ROUSSEL-UCLAF (FR) | 1984-08-01 | — | — | EP | disclosed |