Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.44 |
| ▸ | RELA | Q04206 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994576 | 1.00 | RECQL (0.50) | RECQLMAPTLMNABCHEPLIN1 | |
| SCHEMBL2347397 | 0.82 | HCAR2 (0.53) | LMNATDP1MAPK1 | |
| SCHEMBL5197267 | 0.82 | RECQL (0.55) | RECQLMAPTLMNABCHEPLIN1 | |
| SCHEMBL5704861 | 0.82 | HCAR2 (0.53) | LMNATDP1MAPK1 | |
| SCHEMBL5197269 | 0.82 | RECQL (0.55) | RECQLMAPTLMNABCHEPLIN1 | |
| SCHEMBL5229228 | 0.81 | TDP1 (0.48) | MAPTLMNAHPGDTDP1MAPK1 | |
| SCHEMBL5229224 | 0.81 | TDP1 (0.48) | MAPTLMNAHPGDTDP1MAPK1 | |
| SCHEMBL8403705 | 0.79 | TRPA1 (0.46) | LMNAALDH1A1TDP1 | |
| SCHEMBL29257474 | 0.76 | AKT1 (0.49) | RECQLMAPTLMNABCHEPLIN1 | |
| SCHEMBL13687201 | 0.76 | HCAR2 (0.47) | MAPTLMNAALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4559110-A | REACTING VACUUM DISTILLED PHENYL-PROPRIONALDEHYDE AND ACETOPHENONE, DEHYDRATING PRODUCT WITH ALKALI METAL HYDROXIDE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1985-12-17 | — | — | US | disclosed |