Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229228 | 1.00 | TDP1 (0.48) | TDP1GLATRPA1HCAR2CES2 | |
| SCHEMBL2347397 | 0.86 | HCAR2 (0.53) | TDP1TRPA1HCAR2CES2CES1 | |
| SCHEMBL5704861 | 0.86 | HCAR2 (0.53) | TDP1TRPA1HCAR2CES2CES1 | |
| SCHEMBL8403705 | 0.82 | TRPA1 (0.46) | TDP1TRPA1HCAR2CES2CES1 | |
| SCHEMBL16091083 | 0.82 | PTGS1 (0.59) | TDP1LMNAMAPTCYP2D6HPGD | |
| SCHEMBL28356664 | 0.82 | TDP1 (0.50) | TDP1GLAHCAR2CES2CES1 | |
| SCHEMBL10994576 | 0.81 | RECQL (0.50) | TDP1LMNAMAPTHPGDMAPK1 | |
| SCHEMBL10252950 | 0.81 | HTT (0.39) | LMNAHPGDCYP1A2KMT2A | |
| SCHEMBL11294495 | 0.81 | BRD4 (0.47) | TDP1LMNAMAPTHPGDPOLB | |
| SCHEMBL10994573 | 0.81 | RECQL (0.50) | TDP1LMNAMAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439001-B1 | Process for producing optically active epoxides | TOSOH CORP (JP) | 2007-07-25 | — | — | EP | disclosed |
| EP-1127616-B1 | Catalyst for asymmetric epoxidations of enones and process for producing optically active epoxide employing it | TOSOH CORP (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-1366815-B1 | Catalyst for asymmetric epoxidations of enones and process for producing optically active epoxide employing it | TOSOH CORP (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-6878835-B2 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | TOSOH CORPORATION (JP) | 2005-04-12 | — | — | US | disclosed |
| EP-1439001-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | Tosoh Corporation (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-20040116721-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | TOSOH CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6680275-B2 | COMPLEX OF OPTICALLY ACTIVE BINAPHTHOL, LANTHANUM TRIISOPROPOXIDE OXIDE, TRIPHENYLPHOSPHINE OXIDE AND CUMENE OR TERT-BUTYL HYDROPEROXIDE; OPTICAL PURITY; REACTIVITY; STABILITY | TOSOH CORPORATION (JP) | 2004-01-20 | — | — | US | disclosed |
| EP-1366815-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | Tosoh Corporation (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-20010051737-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | TOSOH CORPORATION (JP) | 2001-12-13 | — | — | US | disclosed |
| EP-1127616-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6201123-B1 | FOR ASYMMETRIC EPOXIDATION OF ENONES; GIVES EPOXIDES HAVING AN ENHANCED OPTICAL PURITY | TECHNO POLYMER CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051737-A1 | Catalyst for asymmetric epoxidation of enones and process for producing optically active epoxide employing it | SQLE, ENO1, GPX4 | TDP1 3343/4885GLA 1549/4885TRPA1 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.