Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994890 | 1.00 | GRM5 (0.57) | GRM5RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL10994182 | 0.91 | GRM5 (0.56) | GRM5RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL10994183 | 0.91 | GRM5 (0.56) | GRM5RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL10992764 | 0.82 | GRM5 (0.56) | GRM5SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL10992762 | 0.82 | GRM5 (0.56) | GRM5SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL10996658 | 0.81 | GRM5 (0.59) | GRM5RAB9ANPC1KDM4EKMT2A | |
| SCHEMBL10996662 | 0.81 | GRM5 (0.59) | GRM5RAB9ANPC1KDM4EKMT2A | |
| SCHEMBL10993124 | 0.79 | GRM5 (0.62) | GRM5RAB9ANPC1KDM4EPOLB | |
| SCHEMBL10993126 | 0.79 | GRM5 (0.62) | GRM5RAB9ANPC1KDM4EPOLB | |
| SCHEMBL11233767 | 0.76 | GRM5 (0.73) | GRM5RAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |