Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993126 | 1.00 | GRM5 (0.62) | GRM5POLBATMRAB9ANPC1 | |
| SCHEMBL10992189 | 0.91 | GRM5 (0.63) | GRM5POLBRAB9ANPC1GAA | |
| SCHEMBL10992172 | 0.91 | GRM5 (0.63) | GRM5POLBRAB9ANPC1GAA | |
| SCHEMBL10997158 | 0.90 | GRM5 (0.56) | GRM5POLBRAB9ATDP1LMNA | |
| SCHEMBL10997160 | 0.90 | GRM5 (0.56) | GRM5POLBRAB9ATDP1LMNA | |
| SCHEMBL10991240 | 0.89 | GRM5 (0.55) | GRM5POLBATMRAB9ANPC1 | |
| SCHEMBL10990477 | 0.88 | GRM5 (0.54) | GRM5POLBATMRAB9ANPC1 | |
| SCHEMBL10992762 | 0.86 | GRM5 (0.56) | GRM5POLBLMNAMEN1KMT2A | |
| SCHEMBL10992764 | 0.86 | GRM5 (0.56) | GRM5POLBLMNAMEN1KMT2A | |
| SCHEMBL10996658 | 0.86 | GRM5 (0.59) | GRM5RAB9ANPC1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |