Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996662 | 1.00 | GRM5 (0.59) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10993124 | 0.86 | GRM5 (0.62) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10993126 | 0.86 | GRM5 (0.62) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10994890 | 0.81 | GRM5 (0.57) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10994893 | 0.81 | GRM5 (0.57) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10992189 | 0.81 | GRM5 (0.63) | GRM5NPC1RAB9AGAA | |
| SCHEMBL10992172 | 0.81 | GRM5 (0.63) | GRM5NPC1RAB9AGAA | |
| SCHEMBL10994183 | 0.80 | GRM5 (0.56) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10994182 | 0.80 | GRM5 (0.56) | GRM5NPC1RAB9AGAAMEN1 | |
| SCHEMBL10997158 | 0.80 | GRM5 (0.56) | GRM5RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |